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Characteristics of LCI of patients with liver cirrhosis who undergo gastric variceal bleeding.
The loss of blood from portal blood vessels of the stomach is referred to as "gastric variceal bleeding." Hepatic encephalopathy (HE) occurs in patients with liver cirrhosis. Recently, the development of brain dysfunction in patients with liver cirrhosis has been associated with the development of HE. Whether the increased levels of serum LCI also play a role in the development of brain dysfunction in patients with liver cirrhosis is unknown. The aim of this study was to investigate the characteristics of serum LCI and its association with HE in patients with liver cirrhosis who undergo gastric variceal bleeding. In total, 82 patients with liver cirrhosis who underwent emergency endoscopic variceal band ligation or endoscopic variceal ligation were enrolled in this study. Patients were divided into two groups based on the Child-Pugh classification: group A (Child-Pugh class A, n=43) and group B (Child-Pugh class B, n=39). Thirty healthy volunteers (control group) were enrolled in this study. Serum LCI levels were higher in patients with liver cirrhosis than in the controls. Serum LCI was significantly higher in patients with Child-Pugh class B than in those with Child-Pugh class A. Serum levels of branched-chain amino acids and urea were significantly higher in group B than in group A. The serum levels of LCI were significantly higher in patients with Child-Pugh class B than in those with Child-Pugh class A. It was suggested that the development of brain dysfunction in patients with liver cirrhosis who undergo gastric variceal bleeding is associated with the increase in the serum levels of LCI.As Seen on TV: Vintage Plaid Blanket
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